Relationship of cataract to radiation sensitivity.
نویسندگان
چکیده
Considerable exposure to radiation always causes posterior subcapsular cataract (PSC). This investigation was conducted to ascertain whether cellular hypersensitivity to radiation may be identified as a possible cause of cataract in persons exposed to low levels of radiation. Patients were studied in whom PSC had followed probable exposure to low levels of radiation or in whom PSC had developed before the age of 60 without known exposure. The patients with cataract were compared with age and sex matched controls without cataract. Radiation sensitivity was estimated by measuring clonal growth of skin fibroblasts and peripheral blood lymphocytes after exposure to graded doses of radiation and by measuring postirradiation reconstruction of separated nuclear material from lymphocytes. The results show variations in the level of radiation sensitivity between the patients, without significant differences from the controls. It is concluded that radiation hypersensitivity, as tested by the methods used in this study, is not normally associated with the development of posterior subcapsular cataract.
منابع مشابه
Measurement of the Adsorbed Radiation Dose to Eyelens During CT Scan and Radiotherapy of Nasopharynx Cancer
Introduction: The study of the cause of death during the last few decades has shown that death due to infectious diseases has been declining and has been rising due to noninvasive diseases, especially cancers and accidents. Cancer is considered as one of the fatal diseases, and every year, more than 10.9 million people worldwide are diagnosed with the disease. Mater...
متن کاملEvaluation of Ferrous-Agarose-Xylenol Gel Properties in Radiation Dosimetry
Background: Over recent decades, modern protocols of external beam radioÂtherapy and radiation techniques such as intensity-modulated radiotherapy (IMRT) have been developed. These methods are extremely sensitive to errors in treatment delivery, so that it is essential to apply a high resolution 3D dosimetry system that has high sensitivity and is capable of measuring and verifying the complex...
متن کاملRisk Relationship of Cataract and Epilation on Radiation Dose and Smoking Habit
An analytic approach that provides explicit estimates of risk on cataract and epilation data is evaluated by reasonableness of conceivable relative risk models regarding a simple, odds, logistic or Gompertz regression method, assuming a binomial distribution. In these analyses, we apply relative risk models with two thresholds between epilators and nonepilators from a highly characteristic lesi...
متن کاملAssessment of Misclassification in a Binary Response: Recovering Information on Clinically Significant Cataract Prevalence from Cataract Surgery Data in Atomic-bomb Survivors
Cataract surgery results when a patient decides to undergo lens surgery following a diagnosis of a clinically significant cataract (CSC). Because the presence of a CSC is generally latent and unobserved, a person might not receive cataract surgery even if the person has a CSC. This misclassification needs to be adjusted in the statistical analysis of CSC so as to reduce the bias in the paramete...
متن کاملDistorted Reflector Antennas: Radiation Pattern Sensitivity to the Surface Distortions
The high-frequency performance of the reflector antennas is mainly limited by the surface. It has been shown that distortions on different regions of the reflector surface can have different effects on the radiation performance. In other words, degradation of the radiation pattern due to the presence of surface distortions is sensitive to the location and behavior of the surface distortion prof...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 73 12 شماره
صفحات -
تاریخ انتشار 1989